Author

Elizabeth A. Griffiths

Roswell Park Comprehensive Cancer CenterORCID 0000-0002-0288-8248Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Abbas Rizvi· 1 shared Alice Brogi· 1 shared Alyssa Clay‐GilmouriD· 1 shared Amy Elizabeth DezerniD· 1 shared Amy WebbiD· 1 shared Carlo FinelliiD· 1 shared Christopher A. HaimaniD· 1 shared Daniel O. StramiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Abbas Rizvi

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2 papers

Recent·Most cited

Unique epigenomic signatures identify biologically significant subtypes of MDS and predict response to azacitidine

Qin Yang, Miguel Torres‐Martín, Masataka Taguchi, Alice Brogi, Irene Casalin, Eleonora Ceneri, Stephanie Halene, Amy Elizabeth Dezern, Elizabeth A. Griffiths, Matilde Y. Follo, Carlo Finelli, Jerald P. Radich, Michael J. Rauh, Rafael L. Bejar, Mikkael Aaron Sekeres, , María E. Figueroa

This study identifies epigenetic subtypes of MDS using DNA methylation patterns and develops a predictive signature for azacitidine response.

bioRxiv · Apr 23, 2025 · PreprintCancer Biology

Genome-wide association analyses identify variants in IRF4 associated with acute myeloid leukemia and myelodysplastic syndrome susceptibility

Junke Wang, Alyssa Clay‐Gilmour, Ezgi Karaesmen, Abbas Rizvi, Qianqian Zhu, Li Yan, Leah M. Preus, Song Liu, Yiwen Wang, Elizabeth A. Griffiths, Daniel O. Stram, Loreall Pooler, Xin Sheng, Christopher A. Haiman, David Van Den Berg, , Lara E. Sucheston‐Campbell

This study identifies IRF4 variants associated with increased risk of de novo AML and MDS through GWAS and TWAS analyses using the DISCOVeRY-BMT cohorts.

Frontiers in Genetics · Jun 17, 2021Peer-reviewedGenomics