Author

Stuart Shapiro

ORCID 0000-0002-4837-7638Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

Adrian John MulhollandiD· 1 shared Catherine L. TookeiD· 1 shared Christopher R. BetheliD· 1 shared JAMES M. SPENCERiD· 1 shared Krisztina M. Papp‐WallaceiD· 1 shared Marc W. van der KampiD· 1 shared Marko HanževačkiiD· 1 shared Michael BeeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adrian John MulhollandORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMar 13, 2025

Mechanistic Basis for Inhibition of the Extended Spectrum Class A b-Lactamase GES-1 by Tazobactam and Enmetazobactam

Michael Beer, Philip Hinchliffe, Marko Hanževački…·JAMES M. SPENCER

This paper investigates how enmetazobactam and tazobactam inhibit GES-1, an ESBL, revealing structural and mechanistic differences in their acyl-enzyme complexes.

DOI 10.1101/2025.03.13.642993

structural biologyexperimental assay

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