Marko Hanževački

Redox Control of S-sulfocysteine Formation in Adenosine Phosphosulfate Reductase

This study investigates how the redox state of an iron-sulfur cluster in APSR from Pseudomonas aeruginosa influences catalytic activity and substrate binding through molecular simulations.

Time-resolved ligand dynamics revealed in a β-lactamase using room-temperature serial crystallography

This study uses room-temperature serial crystallography to observe time-dependent ligand dynamics of the β-lactamase CTX-M-15 with avibactam, revealing conformational changes critical for inhibitor reformation.

Mechanistic Basis for Inhibition of the Extended Spectrum Class A b-Lactamase GES-1 by Tazobactam and Enmetazobactam

This paper investigates how enmetazobactam and tazobactam inhibit GES-1, an ESBL, revealing structural and mechanistic differences in their acyl-enzyme complexes.

Computational investigation of cis-1,4-polyisoprene binding to the latex clearing protein LcpK30

The paper investigates how cis-1,4-polyisoprene binds to LcpK30 using computational methods, identifying two binding modes and hydrophobic tunnels that influence substrate cleavage and product size.