Frido Welker

The paper challenges a model proposing Denisovan AMBN introgression from Homo erectus by showing no signal of super-archaic origin in late Denisovans.

The paper compares proteome composition and modification in different bone types from archaeological human skeletons, finding cortical bone better preserves proteins than trabecular bone and petrous bone has the most complex proteomes.

The paper analyzes archaeological dental enamel proteomes to study the effects of amelogenesis on protein digestion and phosphorylation, and introduces a new marker for estimating genetic sex.

This study identifies dental enamel proteins in ancient human dental calculus, expanding its use beyond diet and microbiome analysis to include sex estimation.

The paper investigates contamination in palaeoproteomic analysis of dental enamel and finds that simple water or bleach washes before demineralization effectively remove contamination without harming endogenous proteins.

This paper demonstrates the successful retrieval of palaeoproteomic data from bone fragments in resin-impregnated sediment blocks, enabling microstratigraphic taxonomic identification of Pleistocene faunal remains.

This study evaluates decontamination methods for ancient proteins, finding that a brief bleach wash effectively removes modern contamination without damaging endogenous proteins from Pleistocene specimens.

The paper analyzes biomolecular data from 39 mammoth individuals to understand Upper Palaeolithic human resource use, finding no sex-based foraging differences in Late Pleistocene megafauna.

The paper identifies a Bronze Age bone tool from the Netherlands as North Atlantic right whale bone using palaeoproteomic methods and finds it was used for plant fibre processing.

MaxNovo is a de-novo peptide sequencing algorithm that outperforms existing methods in high-sensitivity range, using expert knowledge rather than machine learning.

This study uses Early Pleistocene dental enamel proteome sequences to resolve the phylogeny of Stephanorhinus, showing it is paraphyletic and requiring systematic revision.