G-quadruplexes catalyze protein folding by reshaping the energetic landscape
Zijue Huang, Kingshuk Ghosh, Frederick W. Stull, Scott A. Horowitz
The paper shows that G-quadruplexes can catalyze protein folding without ATP, reshaping the energy landscape and suggesting a broader capacity for protein folding in cells.
Proceedings of the National Academy of Sciences · Feb 6, 2025Peer-reviewedBiophysics