Vitamin K-dependent carboxylation in osteoblasts regulates bone resorption through GAS6 in male mice
Monica Pata, Diep Ngoc Thi Pham, Julie Lacombe, B. Ashok Reddy, Young Woong Kim, Abeer Ahmed, Monzur Murshed, Mathieu Ferron
This study identifies GAS6 as a vitamin K-dependent osteoblast-secreted protein that regulates osteoclast maturation and bone mass in male mice.
Bone Research · Apr 27, 2026Peer-reviewedCell Biology