Distinguishing Critical, Beneficial, Neutral and Harmful Mutations Uncovered in the Directed Evolution of a Yeast Membrane Receptor
Adebola Adeniran, Keith E. J. Tyo
The paper identifies critical, beneficial, neutral, and harmful mutations in evolved yeast GPCRs through reversion analysis, revealing shared mechanisms for enhanced peptide detection.
bioRxiv · Aug 4, 2020 · PreprintSynthetic Biology