Nadean L. Brown

Novel Roles of Sonic Hedgehog Signaling in Retinal Patterning and Neurogenesis During Mammalian Eye Development

This study investigates the role of Sonic Hedgehog signaling in retinal development, revealing new functions in optic nerve head identity, nasal-temporal polarity, and coordination of neurogenesis.

Direct comparison of constitutive Rax-Cre transgenic drivers that activate in the mouse embryonic eye field

The paper compares two Rax-Cre transgenic drivers in mice to evaluate their Cre activity in the embryonic eye and extra-ocular tissues.

Notch directs telencephalic development and neuron fate determination by regulating miRNA levels

This study shows Notch signaling regulates miRNA levels to control neuron fate determination and telencephalic development.

Not all Notch pathway mutations are equal in the embryonic mouse retina

The paper investigates Notch pathway mutations in the embryonic mouse retina, finding that Notch signaling is not required for Hes1 sustained expression in the optic stalk/nerve head but has opposing roles in photoreceptor genesis.