Cell BiologybioRxivPreprint
Sequence space of Xpo1-dependent NESs reveals a functional affinity ceiling
Oleh Rymarenko, Trevor Huyton, Dirk Görlich
The paper explores the sequence space of Xpo1-dependent NESs using high-throughput screening and identifies key residues critical for NES activity, revealing an affinity ceiling that explains natural NES limitations.
DOI 10.64898/2026.07.31.742000