Patricio Escalante

Chemokine Signaling Caused by Mycobacterium avium Biofilms in the Lung Airway Increases Bacterial Loads by Spatially Diverting Macrophages

This study uses a computational model to show that MAC biofilms spatially divert macrophages, increasing bacterial loads through chemokine-driven chemotaxis and repeated exposure.

The Role of Biofilms, Bacterial Phenotypes, and Innate Immune Response in Mycobacterium avium Colonization to Infection

This paper develops a 3D agent-based model to simulate early MAC infection dynamics, showing how biofilms and immune responses influence bacterial colonization and infection outcomes.