Author

Kelly M. Pennington

Mayo ClinicORCID 0000-0003-1187-5059Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:simulation· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine WeatherediD· 2 shared Elsje PienaariD· 2 shared Patricio EscalanteiD· 2 shared

Activity by Year

2021-2022 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersSystems Biology

Catherine WeatheredORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintSep 13, 2022

Chemokine Signaling Caused by Mycobacterium avium Biofilms in the Lung Airway Increases Bacterial Loads by Spatially Diverting Macrophages

Catherine Weathered, Kelly M. Pennington, Patricio Escalante, Elsje Pienaar

This study uses a computational model to show that MAC biofilms spatially divert macrophages, increasing bacterial loads through chemokine-driven chemotaxis and repeated exposure.

DOI 10.1101/2022.09.13.507811

statistical modelsimulation

𝕏 PostBluesky

Systems BiologyJournal of Theoretical BiologyPeer-reviewedOct 28, 2021

The Role of Biofilms, Bacterial Phenotypes, and Innate Immune Response in Mycobacterium avium Colonization to Infection

Catherine Weathered, Kelly M. Pennington, Patricio Escalante, Elsje Pienaar

This paper develops a 3D agent-based model to simulate early MAC infection dynamics, showing how biofilms and immune responses influence bacterial colonization and infection outcomes.

14 citations

simulation

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