Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity
Hongjiao Liu, Wodan Ling, Xing Hua, Jee‐Young Moon, Jessica S Williams-Nguyen, Xiang Zhan, Anna Plantinga, Ni Zhao, Angela Yu Zhang, Rob D. Knight, Qibin Qi, Robert David Burk, Robert C. Kaplan, Michael C. Wu
The paper introduces a kernel-based method to identify host genetic variants associated with microbiome beta-diversity, finding immunity-related genes influence gut microbiota composition.
bioRxiv · Oct 15, 2021 · PreprintGenomics