Cancer BiologybioRxivPreprint
B7-H3 as a Dual Clinically Relevant Checkpoint and Antibody Drug Conjugate Target Expressed Across Adenocarcinoma and Neuroendocrine Prostate Cancers
Shivang Sharma, Nikita Mundhara, Emirhan Tekoglu…·Eugene Shenderov
This paper evaluates B7-H3 expression across prostate cancer subtypes and identifies it as a stable target for ADC and ICI due to its low heterogeneity and negative regulation by androgen signaling.
3 citations