Author

Ezra G. Baraban

Johns Hopkins UniversityORCID 0000-0001-6932-8985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Nirmish SinglaiD· 2 shared Adam K. AragakiiD· 1 shared Adrianna Amaral· 1 shared Akinaru Yamamoto· 1 shared Alyssa G. ArbuisoiD· 1 shared Andrés MatosoiD· 1 shared Anne E. GelleriD· 1 shared Archana BalaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Nirmish SinglaORCID

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Author profile →

3 papers

Recent·Most cited

Epithelial to mesenchymal transition and M2 macrophages drive aggressiveness in murine and human sarcomatoid urothelial carcinoma.

Yujiro Hayashi, Roy Elias, Eugene Douglass, Akinaru Yamamoto, Matthew Schuler, Mingxiao Feng, Ekatherina Y. Batourina, Anne E. Geller, Woonyoung Choi, Gabriela Colocho, Alyssa G. Arbuiso, Samuel Jin, Adam K. Aragaki, Charles Ruland, Stanley Rapiey, , Burles Avner Johnson

The paper develops a murine model of sarcomatoid urothelial carcinoma (SUC) and finds it shares molecular and immunological features with human SUC, suggesting its use for therapeutic research.

bioRxiv · Oct 2, 2026 · PreprintCancer Biology

Clear cell renal cell carcinoma consensus transcriptomic programs reveal converging trajectories towards aggressive disease

Roy M. Elias, Vivek Nimgaonkar, Bingrui Emily Xie, Yuqi Zhang, Archana Balan, Kathleen Noller, Nirmish Singla, Yasser M. A. Ged, Ezra G. Baraban, Payal Kapur, James Brugarolas, Genevieve Stein-O’Brien, Michael F. Ochs, Elana Judith Fertig, Atul J Deshpande, Srinivasan Yegnasubramanian

The paper identifies 17 consensus transcriptomic programs in ccRCC using NMF and links them to cellular sources and clinical outcomes, revealing converging trajectories toward aggressive disease.

The Oncologist · Sep 1, 2026Peer-reviewedCancer Biology

B7-H3 as a Dual Clinically Relevant Checkpoint and Antibody Drug Conjugate Target Expressed Across Adenocarcinoma and Neuroendocrine Prostate Cancers

Shivang Sharma, Nikita Mundhara, Emirhan Tekoglu, Adrianna Amaral, Tamara Levin Lotan, Pan Gu, Jun Luo, Ezra G. Baraban, Nathan A. Lack, Eugene Shenderov

This paper evaluates B7-H3 expression across prostate cancer subtypes and identifies it as a stable target for ADC and ICI due to its low heterogeneity and negative regulation by androgen signaling.

bioRxiv · Jan 21, 2025 · PreprintCancer Biology