Single-cell network biology characterizes cell-type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease
Chirag Gupta, Jielin Xu, Ting Jin, Saniya Khullar, Xiaoyu Liu, Sayali Anil Alatkar, Feixiong Cheng, Daifeng Wang
The paper uses single-cell multi-omics data to predict gene regulatory networks in Alzheimer's disease and control, identifying cell-type-specific dysregulation and potential drug targets.
PLoS Computational Biology · Jul 18, 2022Peer-reviewedBioinformatics