NeurosciencebioRxivPreprint
A CRISPR-CAS9 high throughput machine-learning platform for modulation of genes involved in Parkinson's disease-associated PINK1-mitophagy in iPSC-derived dopaminergic neurons
Marc P. M. Soutar, Benedetta Carbone, Petya Kindalova…·Hélène Plun‐Favreau
The paper develops a CRISPR-CAS9 platform with machine learning to study PINK1-mitophagy in Parkinson's disease using iPSC-derived neurons, identifying key genes and validating their roles.
DOI 10.1101/2025.06.10.658840