Author

Lisa Mohamet

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

Benedetta Carbone· 2 shared Aikaterini GeladakiiD· 1 shared Alastair D. ReithiD· 1 shared Alessandro Di Tullio· 1 shared Alice RockliffeiD· 1 shared Andres Quintero Moreno· 1 shared Bin Sun· 1 shared Charlie Haslam· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Benedetta Carbone

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery

Matteo Martufi, Eleni Karagianni, Tasos Papanikos, Tim G. Ashlin, Aikaterini Geladaki, Benedetta Carbone, Katja S. Remlinger, Andres Quintero Moreno, William G. Pembroke, Charlie Haslam, Nico Zinn, Denise F. Vlachou, Margarida Almeida, Dimitrios Tsaousis, Stephan Gade, , Lisa Mohamet

The paper establishes a CRISPR/Cas9 screening platform in hiPSC-derived macrophages to identify genetic targets influencing inflammatory responses and functional phenotypes.

bioRxiv · Sep 14, 2026 · PreprintImmunology

A CRISPR-CAS9 high throughput machine-learning platform for modulation of genes involved in Parkinson's disease-associated PINK1-mitophagy in iPSC-derived dopaminergic neurons

Marc P. M. Soutar, Benedetta Carbone, Petya Kindalova, Rahil Mehrizi, Fernanda Martins Lopes, Nathaniel Lam, Alice Rockliffe, Toni Braybrook, Matthew D. Taylor, Cuong Nguyen, Fiona Ducotterd, Alastair D. Reith, Lisa Mohamet, Hélène Plun‐Favreau

The paper develops a CRISPR-CAS9 platform with machine learning to study PINK1-mitophagy in Parkinson's disease using iPSC-derived neurons, identifying key genes and validating their roles.

bioRxiv · Jun 10, 2025 · PreprintNeuroscience

A Scalable 3D High-Content Imaging Protocol for Measuring a Drug Induced DNA Damage Response Using Immunofluorescent Sub-nuclear γH2AX Spots in Patient Derived Ovarian Cancer Organoids

Hakan Keles, Christopher Schofield, Helena Rannikmäe, Erin Elizabeth Edwards, Lisa Mohamet

This paper develops a scalable 3D imaging protocol to measure DNA damage response in ovarian cancer organoids using γH2AX staining and shows its effectiveness with Etoposide treatment.

ACS Pharmacology & Translational Science · Dec 12, 2022Peer-reviewedBioinformatics