Author

Edward Alain B. Pajarillo

Florida Agricultural and Mechanical UniversityORCID 0000-0002-5044-7607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexis DigmaniD· 1 shared Deok‐Soo SoniD· 1 shared Eun-Sook LeeiD· 1 shared Matthew Dutton· 1 shared Michael AschneriD· 1 shared Sang Hoon KimiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Alexis DigmanORCID

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1 paper

Recent·Most cited

The role of microglial LRRK2 in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction

Edward Alain B. Pajarillo, Sang Hoon Kim, Alexis Digman, Matthew Dutton, Deok‐Soo Son, Michael Aschner, Eun-Sook Lee

This study investigates how manganese exposure increases microglial LRRK2 activity, leading to neuroinflammation and toxicity, with exacerbation in LRRK2 G2019S mutation.

bioRxiv · Apr 3, 2023 · PreprintNeuroscience