Author

Kui Lu

Fudan UniversityORCID 0000-0002-5061-1761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Jinchang LuiD· 1 shared Lina Wang· 1 shared Ning WuiD· 1 shared Shuai NiiD· 1 shared X F Jiang· 1 shared Yun Wang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Jinchang LuORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJul 22, 2026

CESAR: A R Package for High-Sensitivity Detection of Copy Number Variations in ctDNA Using Segmentation and Anchor Recalibration

Jinchang Lu, Shuai Ni, Kui Lu…·X F Jiang

CESAR improves CNV detection in low-tumor fraction ctDNA by recalibrating depth ratios using anchor selection and segmentation, outperforming CNVkit in sensitivity and reproducibility.

1 citation

humanwhole-exome sequencing

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