Atray C. Dixit

DNARecords: An extensible sparse format for petabyte scale genomics analysis

DNARecords introduces a sparse format for large-scale genomics data to improve analysis efficiency and enable integration with diverse data types for disease risk and drug response prediction.

Correcting Chimeric Crosstalk in Single Cell RNA-seq Experiments

The paper addresses chimeric crosstalk in scRNA-seq by proposing supervised and unsupervised computational solutions validated through experiments and replicate PCR amplifications.

Shuffle-Seq: En masse combinatorial encoding for n-way genetic interaction screens

Shuffle-Seq enables large-scale genetic interaction screens by leveraging barcode co-inheritance in dividing cells, applied to study drug resistance mechanisms in melanoma.