ImmunologyFrontiers in ImmunologyPeer-reviewed
Dendritic cell effector mechanisms and tumor immune microenvironment infiltration define TLR8 modulation and PD-1 blockade
Daniel A. Ruiz‐Torres, Jillian Frances Wise, Brian Y. Zhao…·Shannon L. Stott
This study investigates the combination of TLR8 agonism and PD-1 blockade in HNSCC patients, finding increased innate immune activation and dendritic cell-T cell interactions.