Nathan J. Nakatsuka

The paper introduces scSLIDE, a framework that generates sample-level embeddings from single-cell data to analyze variation across samples in disease and development.

The paper develops a meta-analysis method to identify reproducible differentially expressed genes across single-cell transcriptomic case-control studies and finds shared genes across neurodegenerative diseases.

This study evaluates polygenic score models for anthropometric traits and Type II Diabetes in Native Hawaiians, finding reduced accuracy compared to European- or East Asian-ancestry populations.

The paper constructs population-specific recombination maps for Native Hawaiians to improve the accuracy of genomic scans for positive selection.

The paper analyzes ancient genomes from Tiwanaku to show genetic homogeneity in the Lake Titicaca Basin over 1200 years but genetic diversity in ritual core individuals, suggesting foreign influence.

The paper uses ancient DNA data to trace the genetic origins and spread of Indo-European languages in South and Central Asia.