NeurosciencebioRxiv
Structural basis of botulinum neurotoxin serotype A1 binding to human SV2A or SV2C receptors
Fodil Azzaz, Didier Hilaire, Jacques Fantini
This study uses molecular dynamics simulations to elucidate how BoNT/A1 binds to glycosylated SV2A and SV2C receptors in a lipid raft environment, revealing the role of N-glycans in toxin-receptor interactions.
12 citations