Jacques Fantini

The paper shows LGI1 binds gangliosides and may organize lipid platforms for ion channels, and its loss disrupts these platforms in mice.

This paper introduces PS and IIOS, AI tools for analyzing and engineering molecular interactions by decomposing binding interfaces with stage-resolved force-wise insights.

This study analyzed HCoV-OC43 genomes from southern France between 2017-2022, revealing evolutionary dynamics and amino acid substitutions across three genotypes.

This study shows how membrane constraints affect synaptotagmin recognition by botulinum neurotoxin B1 through lipid-mediated interactions, revealing limitations in AI predictions of membrane-bound complexes.

This study tracks long-term SARS-CoV-2 evolution in an immunocompromised patient, identifying mutations and recombination events that drive viral adaptation.

This study uses molecular dynamics simulations to elucidate how BoNT/A1 binds to glycosylated SV2A and SV2C receptors in a lipid raft environment, revealing the role of N-glycans in toxin-receptor interactions.

The paper shows that endocannabinoid-dependent up-regulation of Kv7 channels mediates long-term depression of intrinsic excitability in O-LM interneurons.