Sharona Shleizer-Burko

This study evaluates how promoter proximal short tandem repeats (STRs) affect gene expression using MPRA, identifying key factors like repeat unit sequence and copy number.

The paper develops adVNTR-NN to genotype VNTRs efficiently and identifies eVNTR loci associated with gene expression in multiple tissues.

This study identifies de novo tandem repeat mutations in ASD probands and shows they are more prevalent, larger, and evolutionarily deleterious compared to unaffected siblings.

The paper identifies over 28,000 STRs associated with gene expression across 17 tissues and links them to complex traits like height and schizophrenia.

This paper introduces GangSTR, a tool for genome-wide profiling of tandem repeat expansions, showing it outperforms existing methods and identifies novel expansions in a healthy population.

adVNTR is a method for genotyping Variable Number Tandem Repeats using Hidden Markov Models, applicable to short-read and single molecule sequencing data.