Generation and characterization of a novel mouse model of Becker Muscular Dystrophy with a deletion of exons 52 to 55
Lucie O. M. Perillat, Tatianna Wai Ying Wong, Eleonora Maino, Abdalla Ahmed, Ori Scott, Elzbieta Hyatt, Paul Delgado-Olguı́n, Evgueni A. Ivakine, Ronald D. Cohn
The paper generates a mouse model with an in-frame deletion of exons 52-55 in Dmd, mimicking Becker Muscular Dystrophy, and characterizes its long-term effects on muscle and heart function.
bioRxiv · Nov 16, 2023 · PreprintGenetics