Paul Delgado-Olguı́n

Lipid Nanoparticle Delivery of Mesenchymal Stromal Cell-Derived microRNA 187-3p as a First-in-Class Therapy for Myocardial Dysfunction in Sepsis

This paper demonstrates that lipid nanoparticle-delivered miR-187 reduces inflammation and improves cardiac function in sepsis models.

Molecular and Epigenetic Pathways Underlying Epithelial Damage and Repair in Necrotizing Enterocolitis via Multi-omics Approach

This study uses multi-omics approaches to identify molecular and epigenetic changes in NEC, revealing Ezh2's role in maintaining intestinal stem cells and epithelial regeneration.

Generation and characterization of a novel mouse model of Becker Muscular Dystrophy with a deletion of exons 52 to 55

The paper generates a mouse model with an in-frame deletion of exons 52-55 in Dmd, mimicking Becker Muscular Dystrophy, and characterizes its long-term effects on muscle and heart function.

Irx1 and Irx2 play dose-dependent cooperative functions in mammalian development

This study investigates the dose-dependent cooperative roles of Irx1 and Irx2 in mouse development, revealing distinct phenotypic outcomes from their genetic ablation.

Human - murine concordance of molecular signatures in nerve-sparing murine partial bladder outlet obstruction (NeMO)

This study compares gene expression changes in a nerve-sparing mouse bladder obstruction model (NeMO) with human data, identifying shared cytokine pathways and therapeutic implications.