BiochemistryJournal of Biological ChemistryPeer-reviewed
Branched DNA Processing by a Thermostable CAS-Cas4 from Thermococcus onnurineus: Expanding Biochemical Landscape of Nuclease Activity
M.K. Jain, Asish Kumar Pattnayak, Sakshi Aggarwal…·Vineet Gaur
This paper characterizes the biochemical properties of TON_0321, a CAS-Cas4 protein from Thermococcus onnurineus, revealing its 5' to 3' exonuclease and structure-dependent endonuclease activities.
DOI 10.1016/j.jbc.2025.110701