Author

Alyson Speed

University of CambridgeORCID 0000-0002-5138-2219Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A.R. Phillips· 1 shared Alice T. Browne· 1 shared Carla P. MartinsiD· 1 shared Catherine Joan Davidson· 1 shared Chris McCann· 1 shared Connor N. BrowniD· 1 shared Deborah Y. Moss· 1 shared Donna M. SmalliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A.R. Phillips

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMay 9, 2026

Mutant KRAS dosage contributes to heterogeneity in lung cancer therapeutic response

Alice T. Browne, Chris McCann, William J. McDaid…·Emma M. Kerr

This study shows that mutant KRAS dosage affects therapeutic response in lung cancer, with higher dosages linked to resistance to platinum therapy and sensitivity to pS6K inhibition.

DOI 10.64898/2026.05.06.723208

humanbulk RNA-seq