A Central Role for Canonical PRC1 in Shaping the 3D Nuclear Landscape
Shelagh Boyle, Ilya M. Flyamer, Iain Williamson, Dipta Sengupta, Wendy A. Bickmore, Robert S. Illingworth
This study investigates the role of PRC1 in shaping 3D nuclear organization in mESCs, showing that PRC1-mediated interactions are independent of CTCF and can occur at a megabase scale.
bioRxiv · Dec 15, 2019Molecular Biology