Integrated single-cell whole genome sequencing and spatial transcriptomics reveal latent intra-tumoral heterogeneity in ovarian cancer
Rania Bassiouni, Yuxin Jin, Lee D. Gibbs, Jing Qian, Solomon O. Rotimi, Heather Miller, Michelle G. Webb, Seeta Rajpara, Javier Arias‐Stella, David Wesley Craig, LD Roman, John David Carpten
This study uses single-cell whole genome sequencing and spatial transcriptomics to uncover intra-tumoral heterogeneity in ovarian cancer, revealing evolutionary relationships and functionally consequential copy number alterations.
Cancer Research Communications · Apr 20, 2026Peer-reviewedCancer Biology