Structural serology of polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 COVID-19 vaccines
Sandhya Bangaru, Abigail M. Jackson, Jeffrey Copps, Monica L. Fernández‐Quintero, Jonathan L. Torres, Sara T. Richey, Bartek Nogal, Leigh M. Sewall, Alba Torrents de la Peña, Asma Rehman, Mimi Guebre‐Xabier, Bethany Girard, Rituparna Das, Kizzmekia S. Corbett, Robert A. Seder, , Andrew B. Ward
This study maps polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 vaccines using EMPEM, revealing the NTD supersite as an immunodominant epitope vulnerable to variant mutations.
Cell Reports · Jul 1, 2025Peer-reviewedImmunology