Barney S. Graham

This study shows that Zika virus particles can form without the prM protein and proteolytic activation, and M-E vaccines induce neutralizing antibodies regardless of maturation state.

This study shows that a conventional H1 HA trimer vaccine elicits stem-directed antibodies in rhesus macaques that provide broad protection against H1N1 and H5N1 influenza.

This study identifies mAbs targeting HCoV-HKU1 spike protein and shows that receptor-binding site recognition alone does not predict neutralization in primary cells.

This study identifies human antibodies that broadly inhibit influenza neuraminidase by mimicking its substrate through structural convergence and water-mediated interactions.

This study maps polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 vaccines using EMPEM, revealing the NTD supersite as an immunodominant epitope vulnerable to variant mutations.

This study identifies eight neutralization-sensitive epitopes on Nipah virus F protein using monoclonal antibodies and cryo-electron microscopy, four of which are novel.

Designed trimers matched to viral glycoprotein termini yielded tetrahedral, octahedral and icosahedral nanoparticles with cryo-EM-verified structures that display native-like HIV Env, influenza HA and RSV F.