Abigail M. Jackson

Membrane-bound BG505 MD39.3 Env trimer delivered as mRNA-LNP reduced base-directed antibody responses in rabbits and macaques and elicited neutralizing antibodies, with memory B cell responses documented in macaques.

This study maps polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 vaccines using EMPEM, revealing the NTD supersite as an immunodominant epitope vulnerable to variant mutations.

The paper uses nsEMPEM to analyze polyclonal IgG responses to HA in vaccinated and infected individuals, showing differences in epitope targeting between H1 and H3 subtypes.

QuickFit quantifies viral growth and fitness in vitro using high-throughput RT-qPCR, offering higher throughput and lower error than traditional methods.