Author

Sahand Khakabimamaghani

Simon Fraser UniversityORCID 0000-0002-5178-0188Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Martin EsteriD· 3 shared Alexey SavchikiD· 1 shared Bruno M. GrandeiD· 1 shared Daniel Ziemek· 1 shared Dujian Ding· 1 shared Olga I. IsaevaiD· 1 shared Olga I. ZolotarevaiD· 1 shared Oliver SnowiD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBioinformatics

Martin EsterORCID

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3 papers

Recent·Most cited

Identification of Differentially Expressed Gene Modules in Heterogeneous Diseases

Olga I. Zolotareva, Sahand Khakabimamaghani, Olga I. Isaeva, Zoe S. Chervontseva, Alexey Savchik, Martin Ester

DESMOND identifies differentially expressed gene modules in heterogeneous diseases by integrating gene expression and protein interaction data, improving reproducibility and biological relevance.

Bioinformatics · Dec 2, 2020Peer-reviewedBioinformatics

Uncovering the subtype-specific temporal order of cancer pathway dysregulation

Sahand Khakabimamaghani, Dujian Ding, Oliver Snow, Martin Ester

This paper introduces a mathematical model to identify subtype-specific temporal order of cancer pathway dysregulation and demonstrates its effectiveness on glioblastoma and colorectal adenocarcinoma data.

PLoS Computational Biology · Nov 11, 2019Peer-reviewedBioinformatics

SUBSTRA: Supervised Bayesian Patient Stratification

Sahand Khakabimamaghani, Yogeshwar Kelkar, Bruno M. Grande, Ryan D. Morin, Martin Ester, Daniel Ziemek

SUBSTRA is a Bayesian method for patient stratification that balances predictive performance and interpretability by using regularized biclustering and iterative feature weighting.

Bioinformatics · Feb 15, 2019Peer-reviewedBioinformatics