Severin Berger

This paper develops a framework linking dendritic excitatory-inhibitory balance and branch-specific gating to selective associative memory recall in neural circuits.

Crunch automates ChIP-seq analysis and identifies regulatory motifs, finding that TFs either use single motifs or multiple co-occurring motifs in binding peaks.

This paper introduces a new model for transcription factor binding site prediction that accounts for pairwise dependencies between positions, outperforming existing methods on ChIP-seq and HT-SELEX data.