Cancer BiologybioRxivPreprint
Selective targeting of oncogenic KRAS G12D using peptide nucleic acid oligomers attached to cell-penetrating peptides
Jayati Mondal, Dennis Lam, Mary E. Gerritsen…·Andrew L. Wolfe
This study develops PNA oligomers targeting KRAS G12D mutations with cell-penetrating peptides, showing selective repression of mutant mRNA and protein in cells and efficacy in vivo.
DOI 10.1101/2025.03.28.645837