Pierrick Wainschtein

The paper identifies biases in estimating heritability from ultra-rare variants and shows that accounting for these biases reveals significant heritability estimates for several traits.

The paper reassesses selection on height using GWAS and allele frequency data, finding positive selection at height-associated loci in Europe.

The paper identifies rare variant polygenic risk scores as more effective than common variant polygenic risk scores in identifying individuals with outlier phenotypes in common human diseases and complex traits.

The paper estimates heritability for height and BMI using whole-genome sequence data and finds that rare variants contribute significantly to the missing heritability.