Huanwei Wang

This paper identifies 116 risk loci for melanoma through GWAS, links susceptibility to immunity and Wnt signaling, and develops a PRS improving risk prediction.

The paper identifies biases in estimating heritability from ultra-rare variants and shows that accounting for these biases reveals significant heritability estimates for several traits.

The paper integrates 12 spatial and single-cell technologies to analyze cellular interactions and signatures in three skin cancers, identifying key therapeutic targets and genetic associations.

This study predicts promoter-anchored chromatin interactions using DNA methylation QTL data from a human cohort, finding overlaps with experimental data and associations with complex traits.

This study identifies 143 genetic loci associated with 25 hydroxyvitamin D concentration in Europeans, revealing biological pathways and causal relationships with health outcomes.

This paper introduces SBayesR, a Bayesian method for polygenic prediction using GWAS summary statistics, achieving higher accuracy and efficiency than existing methods.

The paper identifies genetic variants associated with phenotypic variability and shows they exhibit genotype-by-environment interactions for obesity-related traits using UK Biobank data.