Matteo Guardamagna

The emergence of a novel CA1 spatial map requires direct entorhinal input

The paper shows that direct entorhinal input is crucial for CA1 remapping in novel environments, enabling spatial map reorganization.

Toroidal topology of grid-cell activity precedes spatial navigation during development

This study shows that toroidal manifolds in the MEC emerge early in rat pups, preceding spatial experience and exploration, suggesting innate computational motifs in spatial navigation.

Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells

The paper shows that differential phase shifts in grid cell modules enable hippocampal place cell remapping, suggesting a mechanism for orthogonalizing spatial codes during environmental changes.

Direct Entorhinal Control of CA1 Temporal Coding

This study inhibits direct entorhinal inputs to CA1 and finds that theta phase precession is abolished but theta sequences are strengthened, suggesting entorhinal inputs drive learning rather than sequence generation.

State Dependent Coupling of Hippocampal Oscillations

This paper introduces a multivariate analytical framework to study how hippocampal oscillations co-vary and influence neuronal firing during sleep and wakefulness, revealing species-specific network constraints and cross-frequency interactions.

Heterogeneity of network and coding states in CA1

The paper analyzes the heterogeneity of theta sequences and phase precession in CA1 neurons, showing distinct patterns in different cell groups under varying gamma oscillation conditions.

The Hybrid Drive: a chronic implant device combining tetrode arrays with silicon probes for layer-resolved ensemble electrophysiology in freely moving mice

The paper introduces a new chronic implant device for mice that combines tetrode arrays and silicon probes to record layer-resolved neural activity in freely moving animals.