Molecular and cellular dynamics of measurable residual disease progression in myelodysplastic syndromes
Yu-Hsiang Chen, Timothy Bi, Ming qing Xu, Jaehyun Lee, Wesley S. Lu, Mengchuan Zhuang, Alejandro Marinos Velarde, Dustin McCurry, Hui Yang, Gheath Alatrash, Gabriela Rondón, Elizabeth J. Shpall, Fatima Zahra Jelloul, Frances Natalia Cervoni-Curet, Sassine Ghanem, , Pavan Bachireddy
This study identifies molecular features of MRD progression in MDS using single-cell multi-omic profiling, revealing dynamic evolutionary processes and immunoevasive mechanisms.
bioRxiv · Oct 17, 2025 · PreprintCancer Biology