Author

Jaehyun Lee

The University of Texas MD Anderson Cancer CenterPrimary ORCID profile (0009-0001-9871-9704 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Jaehyun LeeiD3 papers · Korean Association Of Science and Technology Studies

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Dustin McCurryiD· 2 shared Jeffrey J. MolldremiD· 2 shared Pavan BachireddyiD· 2 shared Alejandro Marinos VelardeiD· 1 shared Ankit PateliD· 1 shared Bijal Thakkar· 1 shared Catherine J. WuiD· 1 shared Céline KerrosiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Dustin McCurryORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular and cellular dynamics of measurable residual disease progression in myelodysplastic syndromes

Yu-Hsiang Chen, Timothy Bi, Ming qing Xu, Jaehyun Lee, Wesley S. Lu, Mengchuan Zhuang, Alejandro Marinos Velarde, Dustin McCurry, Hui Yang, Gheath Alatrash, Gabriela Rondón, Elizabeth J. Shpall, Fatima Zahra Jelloul, Frances Natalia Cervoni-Curet, Sassine Ghanem, , Pavan Bachireddy

This study identifies molecular features of MRD progression in MDS using single-cell multi-omic profiling, revealing dynamic evolutionary processes and immunoevasive mechanisms.

bioRxiv · Oct 17, 2025 · PreprintCancer Biology

ASXL1 truncating mutations drive leukemic resistance to T cell attack

Dustin McCurry, Zhongqi Ge, Jaehyun Lee, Rishi Pasumarthi, Xiaohong Leng, Thomas Köhnke, Oren Pasvolsky, Pranaya Raparla, Vinhkhang N. Nguyen, Katie Maurer, Shuqiang Li, Kenneth J. Livak, Emerie E Danson, Bijal Thakkar, Elham Azizi, , Pavan Bachireddy

This study identifies ASXL1 truncating mutations as a driver of leukemic resistance to T cell attack and proposes EZH2 inhibition as a therapeutic strategy to overcome this resistance.

bioRxiv · May 29, 2025 · PreprintCancer Biology