Qianqian Shi

This paper introduces SpaSRL, a method for spatial domain detection and spatial functional genes identification in spatial transcriptomics, showing improved performance across multiple datasets.

This study shows that D2 dopamine receptors in the superior colliculus modulate defensive behaviors to visual threats, with optogenetic activation promoting defensive responses and chemogenetic inhibition reducing them.

LANTSA improves analysis of scRNA-seq and spatial transcriptomics data by addressing cross-platform and large-volume challenges through a novel subspace model and dimensionality reduction technique.

This study identifies genes associated with different stages of Parkinson's disease pathogenesis using longitudinal blood transcriptome analysis and suggests candidate drugs for each phase.