Author

Laura E. Raffals

Mayo ClinicORCID 0000-0002-5267-2592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A Li· 1 shared Adam L. EdwinsoniD· 1 shared Aditya Vijay BhagwateiD· 1 shared Ailsa L HartiD· 1 shared Ajay Verma· 1 shared Alan Steel· 1 shared Alana English· 1 shared Alexander RevziniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

A Li

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 23, 2026

Resolving inflammatory bowel disease risk variants to genes and cell types

Laura Fachal, Rui Zhang, Kyle Gettler…·Judy H. Cho

This study identifies 619 IBD risk signals, resolves 81 high-confidence variants, and prioritizes 664 candidate effector genes using GWAS, eQTL, and exome sequencing.

DOI 10.64898/2026.05.13.26352926

humanGWAS summary statistics

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Molecular BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2026

Intestinal Stem Cells from Patients with Inflammatory Bowel Disease Retain an Epigenetic Memory of Inflammation

Feda H. Hamdan, Mona Farhadipour, Isaiah Pérez…·Brooke R. Druliner

This study shows that intestinal stem cells from IBD patients retain epigenetic memory of inflammation, leading to heightened responses to future injury but also increased risk of relapse.

10 citationstop 1%

humanbulk RNA-seq

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