Author

Jan Grimm

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-5282-9385Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jan Grimm1 paper · University of Zurich

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Elana Apfelbaum· 3 shared Ali Yasin SonayiD· 2 shared Benedict Mc LarneyiD· 2 shared Charlene Hsu· 1 shared Elizabeth L. IsaaciD· 1 shared Federica Piccardi· 1 shared Nermin Mostafa· 1 shared Nermin Mustafa· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

Elana Apfelbaum

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Author profile →

3 papers

Recent·Most cited

Sustained Ion Imbalances Enhance Ferroptosis

Ali Yasin Sonay, Elana Apfelbaum, Nermin Mustafa, Jan Grimm

This study identifies ion imbalances as a factor in ferroptosis, showing that modulators of ion channels can enhance ferroptotic cell death and reduce tumor growth.

bioRxiv · Oct 1, 2026 · PreprintCancer Biology

ENHANCING TUMOR PERFUSION AND NANOMEDICINE DELIVERY VIA ENDOGENOUS NITRIC OXIDE RELEASE BY METHYL PALMITATE NANOPARTICLES

Roberto Palomba, Elizabeth L. Isaac, Raffaele Spanò, Federica Piccardi, Benedict Mc Larney, Elana Apfelbaum, Nermin Mostafa, Charlene Hsu, Jan Grimm, Paolo Decuzzi

This study shows that methyl palmitate nanoparticles enhance tumor perfusion and nanomedicine delivery by inducing vasodilation and reducing phagocytosis.

bioRxiv · Mar 4, 2026 · PreprintBioengineering

In vivo imaging of ferroptosis through nanodynamic changes in lipid membranes

Ali Yasin Sonay, Elana Apfelbaum, Benedict Mc Larney, Jan Grimm

The paper identifies phosphatidyl serine exposure as a marker for imaging ferroptosis and demonstrates that the dye CJ215 can label ferroptotic cells in vitro and in vivo.

npj Imaging · Oct 6, 2025Peer-reviewedCancer Biology