PhysiologyNature MetabolismPeer-reviewed
Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control
Julien Chilloux, François Brial, Amandine Everard…·Marc‐Emmanuel Dumas
This study identifies trimethylamine (TMA) as a microbial compound that inhibits IRAK4, reducing inflammation and improving metabolic outcomes in high-fat diet conditions.
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