Mark Thomas Harnett

This paper shows that plateau potentials in mouse visual cortex drive single-trial synaptic plasticity, enabling rapid reshaping of sensory representations.

Patch2MAP integrates patch-clamp electrophysiology with super-resolution imaging to analyze subcellular protein expression in human neurons without genetic modification.

This study shows that mouse retrosplenial cortex uses recurrent neural dynamics to form and refine internal hypotheses for spatial reasoning based on ambiguous landmarks.

CLOOSE provides an open-source platform for optical closed-loop experiments, enabling real-time data processing and neurofeedback with functional imaging data.

This study shows that visual landmarks become more represented in mouse retrosplenial cortex during spatial learning, with stable activity patterns and context-dependent coding.

This paper shows how cortical pyramidal neurons balance synaptic flexibility and stability by differentially regulating plasticity at oblique and basal dendrites.

This study shows that head direction representations in mouse retrosplenial cortex and anterodorsal thalamus are coordinated during visual cue rotation and maintained in darkness.

The paper tests for vectorized instructive signals in dendrites during a BCI task and finds that dendritic signals contain task-related information and disrupt learning when perturbed.

The paper introduces ONIX, a system for long-duration neural recordings during natural behavior in mice, enabling high-throughput data acquisition with minimal behavioral impact.

The paper examines 1/f aperiodic activity in cortical layers across species, finding steeper slopes and greater magnitudes in superficial layers.

This study investigates how visual landmarks are represented in the retrosplenial cortex using a behavioral task and two-photon imaging in mice.

Twister3 is a fast, repeatable, open-source microwire twisting machine for neural probes.

The paper describes a lightweight, robust tetrode drive implant for chronic recordings in freely moving animals, improving data yield through design optimization.

This paper introduces a rotational head-fixation system for 2-photon imaging that allows mice to rotate their heads during 2D navigation, enabling more natural behaviors while maintaining subcellular imaging resolution.