Molecular BiologybioRxivPreprint
Interleukin-4 suppresses TIMP-2 transcription during endometriosis: Allele-specific regulation of the TIMP-2 -418G/C promoter by SP1
Susmita Saha, Supratim Ghosh, Tapasi Roy…·Snehasikta Swarnakar
This study identifies an IL-4-SP1-TIMP-2 regulatory axis that contributes to ECM dysregulation in endometriosis and shows the TIMP-2 -418G/C promoter polymorphism affects cytokine-mediated transcription.
DOI 10.64898/2026.10.15.759364