Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model
Veronica Lentini, Giuseppe Uras, Alessia Manca, Mohammed Amine El Faqir, Sara Lucas Del Pozo, Nicola Deiana, Giacomo Cao, Anthony H.V. Schapira, Antonella Pantaleo
This study shows that simulated microgravity accelerates alpha-synuclein aggregation and oxidative stress in Parkinson's disease cell models, mimicking aging-related stress.
bioRxiv · Oct 25, 2024 · PreprintNeuroscience