Christopher Riccardi

Engineering the Marine Pseudoalteromonas haloplanktis TAC125 via pMEGA Plasmid Targeted Curing Using PTasRNA Technology

This study cures the pMEGA plasmid from PhTAC125 using PTasRNA technology, resulting in a strain with enhanced oxidative stress resistance and reduced biofilm formation.

The acquisition of additional control over quorum sensing regulation buffers noise in microbial growth dynamics

This study shows that acquiring additional quorum sensing modules reduces population size variability in Burkholderia by buffering noise in growth dynamics.

Metabolic robustness to growth temperature of cold adapted bacterium

The paper investigates metabolic robustness and transcriptomic reprogramming in a cold-adapted bacterium at different temperatures, revealing key intermediates and pathway cross-talk involved in adaptation.

The selective force driving metabolic genes clustering

The paper argues that DNA replication and cell division coupling introduces a selective force driving metabolic gene clustering, which is a preliminary step in operon formation.

Modelling the metabolic consequences of antimicrobial exposure

The paper investigates how antimicrobial exposure affects bacterial metabolism using transcriptomics and computational modeling, finding that experimental conditions influence metabolic networks more than antimicrobial type, but common metabolic strategies exist.

Extraction and analysis of methylation features from Pacific Biosciences SMRT reads using MeStudio

The paper introduces MeStudio, a tool for analyzing DNA methylation from SMRT sequencing data, and demonstrates its application on bacterial genomes.